3-(2-HYDROXYETHYL)-2-OXAZOLIDINONE synthesis
- Product Name:3-(2-HYDROXYETHYL)-2-OXAZOLIDINONE
- CAS Number:3356-88-5
- Molecular formula:C5H9NO3
- Molecular Weight:131.13
111-42-2
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105-58-8
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$15.00/25g
3356-88-5
63 suppliers
$60.00/500mg
Yield:3356-88-5 99%
Reaction Conditions:
in ethylene glycol at 98 - 103; for 12.5 h;Conversion of starting material;
Steps:
32
N-(2-hydroxyethyl)-2-oxazolidinone Starting Materials Diethly carbonate 1.1 mol (130 g) Diethanolamine 0.955 mol (100 g) Ethylene Glycol 230 g. Operating Conditions Pressure Atmospheric Temperature/time regime 98-103° C./12.5 h Reaction Progress Monitored by TLC and using a spot test for diethanolamine (sodium nitroferricyanide/acetaldehyde/aqueous sodium carbonate) Work-up By-product ethanol, excess diethyl carbonate and ethylene glycol (291 mL) were separated from product by distilling at atmospheric pressure first and then at about 20 mm Hg at 25° C. The product fraction weighed 123.9 g, (refraction index 1.482) (literature 1.483) Yield 99%
References:
US2005/27120,2005,A1 Location in patent:Page/Page column 12
201230-82-2
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111-42-2
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$10.00/20mg
3356-88-5
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$60.00/500mg
1072-52-2
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124-38-9
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$214.00/14L
3356-88-5
63 suppliers
$60.00/500mg
124-38-9
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$214.00/14L
111-42-2
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$10.00/20mg
115-19-5
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3356-88-5
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$60.00/500mg
115-22-0
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![2-Oxazolidinone, 3-[2-(phenylmethoxy)ethyl]-](/CAS/20210111/GIF/864376-06-7.gif)
864376-06-7
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3356-88-5
63 suppliers
$60.00/500mg