3,4-Diaminothiophene dihydrobromide synthesis
- Product Name:3,4-Diaminothiophene dihydrobromide
- CAS Number:78637-85-1
- Molecular formula:C4H6N2S
- Molecular Weight:114.17
3141-26-2
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$5.00/1g
78637-85-1
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$45.00/50mg
Yield: 94%
Reaction Conditions:
with [Cu2(2,7-bis(pyridin-2-yl)-l,8-naphthyridine)(OH)(CF3COO)3];tetrabutylammomium bromide;ammonia;caesium carbonate in ethylene glycol at 140; for 16 h;Sealed tube;chemoselective reaction;
Steps:
2.2 General procedure for amination
General procedure: A mixture of substrate (0.25 mmol), complex 1 (2.5 × 10- 3 mmol), Cs2CO3 (1 mmol), Conc. NH3(aq) (0.5 mL) and TBAB (0.25 mmol) in water (0.5 mL) were loaded in a sealed reaction tube. The reaction temperature was increased to 110-140 °C and the reaction mixture was stirred for 8-24 h. After cooling to RT, the reaction mixture was poured into a saturated NaCl solution, extracted with ethyl acetate and dried over anhydrous MgSO4. After removal of solvents, the residue was re-crystallized or chromatographed on silica gel. All products were characterized by NMR spectroscopy and were consistent with the literature data.
References:
Liao, Bei-Sih;Liu, Shiuh-Tzung [Catalysis Communications,2013,vol. 32,p. 28 - 31]
52431-30-8
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78637-85-1
68 suppliers
$45.00/50mg
90069-81-1
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$18.00/100mg
78637-85-1
68 suppliers
$45.00/50mg