3-BROMOQUINOLIN-2(1H)-ONE synthesis
- Product Name:3-BROMOQUINOLIN-2(1H)-ONE
- CAS Number:939-16-2
- Molecular formula:C9H6BrNO
- Molecular Weight:224.05
22615-00-5
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$45.00/100mg
939-16-2
83 suppliers
$90.00/50mg
Yield: 90%
Reaction Conditions:
with zinc dibromide in toluene for 3 h;Irradiation;
Steps:
3 Example 3: Synthesis of 3-bromo-2-quinolinone (1c)
Accurately weigh the reaction substrate 3-bromoquinoline-N-oxide (223.0 mg, 1.0 mmol) and zinc bromide (1 mol%, 2.3 mg) into a quartz reactor, add 0.5 ml of toluene, under air conditions. After reacting for 3 hours under a xenon lamp irradiation, toluene was removed by a rotary evaporator, and purified by silica gel column chromatography (petrole ether: ethyl acetate = 2:1) to obtain a reaction product. The product was a white powdery solid in a yield of 90% (154.4 mg).
References:
Dalian University of Technology;Yu Xiaoqiang;Bao Ming;Feng Xiujuan;Yang Sana CN108794395, 2018, A Location in patent:Paragraph 0035; 0036; 0037; 0038
5332-24-1
373 suppliers
$10.00/5g
939-16-2
83 suppliers
$90.00/50mg
22615-00-5
47 suppliers
$45.00/100mg
939-16-2
83 suppliers
$90.00/50mg
![Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-](/CAS/20210305/GIF/1000210-73-0.gif)
1000210-73-0
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