一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List 3-Dimethylaminophenol
99-07-0

3-Dimethylaminophenol synthesis

11synthesis methods
3-Dimethylaminophenol is used to synthesize dyes and pharmaceutical intermediates. The traditional production process of this compound is to react m-aminophenol with dimethyl sulfate and then purify it in multiple steps to obtain 3-(N, N-dimethylamino)phenol. The production process requires highly toxic dimethyl sulfate, which has high requirements for safe production and raw material transportation and is not conducive to industrial production. Another method is to first react resorcinol with dimethylamine aqueous solution to obtain 3-(N, N-dimethylamino)phenol crude product, then add industrial liquid alkali to the crude product, and then add toluene to extract by-products. After neutralising the aqueous phase, wash to remove the unreacted resorcinol and then distil under reduced pressure to obtain 3-(N, N-dimethylamino)phenol. The operation is simple, the product purity is high, the raw materials are easy to store and transport, and it is easy to industrialize and produce safely.
-

Yield:99-07-0 93%

Reaction Conditions:

with hydrogen in water at 200; under 375.038 Torr; for 3 h;Autoclave;Reagent/catalyst;

Steps:

2. Experimental section
General procedure: General procedure for the amination of resorcinol with secondaryamine catalyzed by Raney Ni. Resorcinol (2.2 g, 20 mmol), secondaryamine (30 mmol) and Raney Ni (110 mg) were added to water(50 ml) in a 100 ml autoclave. The autoclave was purged with hydrogengas three times, then maintained 0.05 Mpa pressure. The mixturewas heated to 200 °C rapidly. Then stirring was maintained for 3 h.The reaction mixture was cooled to room temperature, and then extractedwith N-butyl acetate. The organic layer was dried (MgSO4), filteredand concentrated to give the crude product. The pure productwas got through flash column chromatography on silica gel (petroleumether/acetylacetic ester (3/1, v/v)).

References:

Ge, Xin;Pan, Jiong-Bin;Qian, Chao;Feng, Lie;Chen, Yun-Bin;Chen, Xin-Zhi [Catalysis Communications,2014,vol. 46,p. 201 - 207]

FullText

3-Dimethylaminophenol Related Search:

永德县| 东乡族自治县| 阿拉尔市| 华亭县| 绥芬河市| 江西省| 夏津县| 大关县| 昌都县| 晋宁县| 广宗县| 平罗县| 象山县| 容城县| 香港 | 外汇| 伊宁市| 裕民县| 乌鲁木齐市| 徐水县| 墨竹工卡县| 海盐县| 吴堡县| 理塘县| 天台县| 贡觉县| 泸定县| 林口县| 呈贡县| 庐江县| 榆中县| 鹤庆县| 濮阳市| 梅河口市| 西藏| 徐闻县| 莱芜市| 武川县| 民丰县| 绥阳县| 朝阳县|