一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List 3-Fluoro-4-nitrobenzoic acid
403-21-4

3-Fluoro-4-nitrobenzoic acid synthesis

5synthesis methods
To a solution of 3-fluoro-4-nitrobenzyl alcohol (2.97 g) in acetone (60 ml) was added Jones reagent (13 ml), prepared from chromic acid (26.7 g) and sulfuric acid (23 ml) in water (100 ml), dropwise at 0°C. The mixture was stirred on a ice-bath for 0.5 h and quenched with isopropanol (20 ml) to be concentrated in vacuo. The residue was dissolved in ethyl acetate (30 ml) and washed with water (30 ml X 3), and brine (30 ml X 1), successively. The organic layer was dried over sodium sulfate and concentrated in vacuo to obtain a yellow solid, that was triturated with hexane. 3-fluoro-4-nitrobenzoic acid as a pale yellow solid (2.94 g, 92%).
3-Fluoro-4-nitrobenzoic acid synthesis
-

Yield:403-21-4 83%

Reaction Conditions:

with potassium dichromate;sulfuric acid in acetic acid at 120; for 2 h;

Steps:

445
2-Fluoro-4-methyl-l-nitro-benzene (1.0 g, 12.9 mmol) was added portion- wise to a suspension of potassium dichromate (5.04 g, 17.16 mmol) in glacial acetic acid (8 mL) follow by concentrated sulfuric acid (3.6 mL). The reaction mixture was heated to 1200C for 2 h and then allowed to cool to ambient temperature. The reaction was quenched with crushed ice and extracted with ethyl acetate. The organic layer was washed with brine, dried over anhydrous sodium sulfate and concentrated in vacuo to afford 3-fluoro-4-nitro-benzoic acid (1.9 g, 83%) as a white solid.

References:

F2G LTD WO2009/130481, 2009, A1 Location in patent:Page/Page column 145

FullText

3-Fluoro-4-nitrobenzoic acid Related Search:

海原县| 兴隆县| 平遥县| 凤冈县| 丰台区| 绍兴县| 洪雅县| 镇雄县| 潮州市| 麻江县| 巩留县| 罗定市| 崇文区| 平南县| 安新县| 龙州县| 台州市| 景宁| 凤城市| 寻甸| 吉首市| 左权县| 沈丘县| 喀喇| 莱西市| 武乡县| 定陶县| 都匀市| 金坛市| 肥西县| 临沭县| 九寨沟县| 呼玛县| 元阳县| 泊头市| 巴林左旗| 咸丰县| 邓州市| 衡阳县| 汕尾市| 济宁市|