一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List N-(3-METHOXYPHENYL)-3-NITRO-4-(1H-PYRAZOL-1-YL)BENZENECARBOXAMIDE
321534-62-7

N-(3-METHOXYPHENYL)-3-NITRO-4-(1H-PYRAZOL-1-YL)BENZENECARBOXAMIDE synthesis

1synthesis methods
-

Yield:-

Reaction Conditions:

Stage #1: m-Anisidinewith dmap;1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane at 20; for 0.0833333 h;
Stage #2: C10H7N3O4 in dichloromethane at 20; for 18 h;

Steps:

General procedure for benzanilides or nicotinanilides 3-5, 7a-7e, 8a-8d, 8f-8k, 9a, 9c-9n, 11

To a solution of 1.5 mmol N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride (EDC·HCl) and 1 mmol 4-dimethylaminopyridine (DMAP) in 2 ml dichloromethane were added 1.5 mmol 3-substituted aniline and the solution stirred at ambient temperature for 5 min. This solution was then added to 1 mmol of substituted benzoic or nicotinic acid and the solution stirred at ambient temperature for 18 hours. The reaction mixture was filtered through a cartridge filled with 5g SCX/silica gel 2:3, pre-washed with 10 ml methanol and 20 ml dichloromethane, and the reaction product eluted with 50 ml dichloromethane. Evaporation provided the benzanilides or nicotinanilides typically as solids.

References:

Stalder, Henri;Hoener, Marius C.;Norcross, Roger D. [Bioorganic and Medicinal Chemistry Letters,2011,vol. 21,# 4,p. 1227 - 1231] Location in patent:supporting information; experimental part

佛教| 正镶白旗| 大丰市| 日土县| 土默特右旗| 兰州市| 玉屏| 广昌县| 合江县| 汝州市| 晋中市| 渭南市| 双柏县| 德钦县| 兰州市| 台北市| 德格县| 日土县| 铜陵市| 永善县| 永善县| 水富县| 忻城县| 望奎县| 彝良县| 阿坝县| 海丰县| 洪泽县| 高淳县| 长岛县| 铁力市| 汝南县| 金昌市| 小金县| 望城县| 天水市| 上思县| 丽江市| 北海市| 天祝| 安康市|