4-(2-BROMOPROPANOYL)MORPHOLINE synthesis
- Product Name:4-(2-BROMOPROPANOYL)MORPHOLINE
- CAS Number:2620-13-5
- Molecular formula:C7H12BrNO2
- Molecular Weight:222.08
Yield:2620-13-5 206 g
Reaction Conditions:
with triethylamine in acetone at 7; for 4 h;Temperature;Reagent/catalyst;Solvent;
Steps:
1.1
(1) 300g of acetone was added in the four-necked flask, 91g morpholine, morpholine formulated as a solution.171g of 2-bromo-propionyl chloride was dissolved in 200g of acetone formulated into a solution of 2-bromo propionyl chloride, 2-bromo propionyl chloride solution was dropwise added to the above solution, morpholine, 100g of triethylamine was added, at 7 conditions for 4 hours.(2) extraction step (a) the reaction product of supernatant vacuum distillation, collecting distillate 206g 180 ~ 185 , namely the product of 2-bromo-propionyl morpholine
References:
CN104628678,2016,B Location in patent:Paragraph 0038; 0039
