4-BENZOYLPIPERIDINE HYDROCHLORIDE synthesis
- Product Name:4-BENZOYLPIPERIDINE HYDROCHLORIDE
- CAS Number:25519-80-6
- Molecular formula:C12H16ClNO
- Molecular Weight:225.72
193217-39-9
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$75.00/100mg
25519-80-6
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$22.32/Price $/250mgs:
Yield:25519-80-6 98%
Reaction Conditions:
with hydrogenchloride in 1,4-dioxane at 18 - 25; for 0.5 h;
Steps:
To this oil was added HCl (2.59 mL, 10.4 ?αnol, 4M in dioxane) and the solution was stirred for 30 minutes at room temperature. The solvent was removed in vacuo to give phenyl (piperidin-4-yl)methanone hydrochloride (0.023 g, 98%) as a solid: 1H NMR (400 MHz, DMSO- d6) δ 1.75 (m, 2H), 1.95 (m, 2H), 3.04 (m, 2H), 3.48 (m, 2H), 3.69 (m, 2H), 3.77 (m, IH), 7.56 (m, 2H), 7.68 (m, IH), 8.00 (m, 2H) .
References:
TAKEDA PHARMACEUTICAL COMPANY LIMITED WO2008/11130, 2008, A2 Location in patent:Page/Page column 147
25519-79-3
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25519-80-6
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25503-90-6
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$5.00/1g
25519-80-6
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$22.32/Price $/250mgs:
498-94-2
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$5.00/10g
25519-80-6
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59084-16-1
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$14.14/250mgs:
25519-80-6
103 suppliers
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