(4-BroMophenyl)(4-Methylphenyl)Methanol synthesis
- Product Name:(4-BroMophenyl)(4-Methylphenyl)Methanol
- CAS Number:29334-17-6
- Molecular formula:C14H13BrO
- Molecular Weight:277.1564
5084-80-0
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1122-91-4
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29334-17-6
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$95.00/250mg
Yield:29334-17-6 92%
Reaction Conditions:
with C42H62ClO3PPd;sodium phosphate in toluene at 50; for 36 h;
Steps:
General procedure for palladacycle 1-catalyzed addition reactions of arylboroxines with aldehydes
General procedure: To a vial containing aldehyde (0.25 mmol), arylboroxine (0.167 mmol), K3PO4 (0.75 mmol) and palladacycle 1 (0.00125-0.0000125 mmol) (palladacycle 1 was added in a toluene solution: 1 mg/mL solution of palladacycle 1 in toluene was freshly prepared and 1-40 μL of this solution was added to the reaction system by microsyringes) was added toluene (1 mL). After the mixture was stirred at 50-90 oC for 20-60 hours, the reaction was quenched by adding a small amount of water. Column chromatography on silica gel with ethyl acetate/hexane (v/v=1:10) afforded the alcohols.
References:
Liao, Yuan-Xi;Xing, Chun-Hui;Israel, Matthew;Hu, Qiao-Sheng [Tetrahedron Letters,2011,vol. 52,# 26,p. 3324 - 3328] Location in patent:supporting information; experimental part
5720-05-8
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$5.00/1g
1122-91-4
715 suppliers
$9.00/10g
29334-17-6
20 suppliers
$95.00/250mg
589-87-7
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104-87-0
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$6.00/25g
29334-17-6
20 suppliers
$95.00/250mg
106-38-7
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$14.00/5g
1122-91-4
715 suppliers
$9.00/10g
29334-17-6
20 suppliers
$95.00/250mg