(4-CHLOROPHENYLTHIO)ACETONE synthesis
- Product Name:(4-CHLOROPHENYLTHIO)ACETONE
- CAS Number:25784-83-2
- Molecular formula:C9H9ClOS
- Molecular Weight:200.69
1142-19-4
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$27.00/10g
598-31-2
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$60.00/50mg
25784-83-2
76 suppliers
$20.00/5g
Yield: 86%
Reaction Conditions:
with [{Ti(salophen)H2O}2O][OSO2C4F9]2;zinc in tetrahydrofuran at 20; for 3 h;Inert atmosphere;
Steps:
4.4. Typical procedure for the synthesis of a-arylthio carbonylcompounds
General procedure: Under N2 atmosphere, a solution of complex 1 (68.7 mg, 5 mol%) in THF (3.0 mL), zinc dust (80 mg, 1.2 mmol), diphenyl disulfide (109 mg, 0.5 mmol), and ethyl 2-bromoacetate (184 mg, 1.1 mmol) were added. Then the mixture was stirred for 2 h at room temperature, monitored by thin-layer chromatography (TLC). The resulting reaction mixture was diluted with diethyl ether (10 mL x 3), filtered, and evaporated, and then the residue was subjected to column chromatography using petroleum ether:ethyl acetate as eluent (30:1) to afford the pure product 6a.
References:
Wang, Lingxiao;Qiao, Jie;Wei, Jiancong;Liang, Zhiwu;Xu, Xinhua;Li, Ningbo [Tetrahedron,2020,vol. 76,# 4,art. no. 130750]
1142-19-4
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$27.00/10g
67-64-1
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$17.30/10ml
25784-83-2
76 suppliers
$20.00/5g
106-54-7
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$10.00/5g
25784-83-2
76 suppliers
$20.00/5g
106-46-7
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$10.00/5g
25784-83-2
76 suppliers
$20.00/5g