(4-FLUORO-PHENYL)-PROPYNOIC ACID ETHYL ESTER synthesis
- Product Name:(4-FLUORO-PHENYL)-PROPYNOIC ACID ETHYL ESTER
- CAS Number:1736-31-8
- Molecular formula:C11H9FO2
- Molecular Weight:192.19
Yield:1736-31-8 96%
Reaction Conditions:
Stage #1: 1-ethynyl-4-fluorobenzenewith n-butyllithium in tetrahydrofuran;hexane at -78; for 1.5 h;Inert atmosphere;
Stage #2: chloroformic acid ethyl ester in tetrahydrofuran;hexane at 20; for 19 h;Inert atmosphere;
References:
O'Rourke, Natasha F.;Wulff, Jeremy E. [Organic and Biomolecular Chemistry,2014,vol. 12,# 8,p. 1292 - 1308]
1999-00-4
222 suppliers
$13.00/1g
1736-31-8
23 suppliers
$501.61/5MG
1765-93-1
563 suppliers
$9.00/1g
623-47-2
347 suppliers
$10.00/1g
1736-31-8
23 suppliers
$501.61/5MG
