4-N-HEXYLOXYBENZONITRILE synthesis
- Product Name:4-N-HEXYLOXYBENZONITRILE
- CAS Number:66052-06-0
- Molecular formula:C13H17NO
- Molecular Weight:203.28
111-25-1
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$10.00/5g
767-00-0
584 suppliers
$6.00/25g
66052-06-0
32 suppliers
$110.00/50mg
Yield:66052-06-0 100%
Reaction Conditions:
in potassium carbonate;
Steps:
34.A A.
A. 4-(Hexyloxy)Benzonitrile A solution of 4-cyanophenol (20 g, 168 mmol) in dimethylformamaide was treated with potassium carbonate (2 eq., 338 mmol, 47 g) and 1-bromohexane (1.1 eq., 185 mmol, 35 mL) and stirred at room temperature for 18 hours. The solid was filtered off and the solution was partitioned between ethyl acetate and 1 N HCl. The organic phase was washed with brine, dried over MgSO4, filtered and the solvent was removed to give compound 2 (45 g, >100%).
References:
US2002/137968,2002,A1
767-00-0
584 suppliers
$6.00/25g
111-27-3
555 suppliers
$5.00/25g
66052-06-0
32 suppliers
$110.00/50mg
623-03-0
477 suppliers
$6.00/25g
111-27-3
555 suppliers
$5.00/25g
66052-06-0
32 suppliers
$110.00/50mg
623-00-7
494 suppliers
$6.00/10g
111-27-3
555 suppliers
$5.00/25g
66052-06-0
32 suppliers
$110.00/50mg
623-00-7
494 suppliers
$6.00/10g
66052-06-0
32 suppliers
$110.00/50mg