ethyl 2-oxo-2,3-dihydro-1H-benzo[d]iMidazole-1-carboxylate synthesis
- Product Name:ethyl 2-oxo-2,3-dihydro-1H-benzo[d]iMidazole-1-carboxylate
- CAS Number:41120-23-4
- Molecular formula:C10H10N2O3
- Molecular Weight:206.2
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Yield:41120-23-4 100%
Reaction Conditions:
with potassium carbonate in acetonitrile; for 2 h;Heating / reflux;
Steps:
Ethyl 2-oxo-2,3-dihydrobenzimidazole-1 -carboxylate (IV); A mixture of 11.0 g (39.5 mmol) of diethyl 2-oxobenzimidazole-1 ,3-dicarboxylate (III), 5.30 g (39.5 mmol) of 2-hydroxybenzimidazole and 6.55 g (47.4 mmol) of potassium carbonate in acetonitrile (200 ml) was heated under reflux with vigorous stirring for 2 h. Most of the solvent was then removed in vacuo, and the residue was mixed with 150 ml of 1 N hydrochloric acid. The solid residue was filtered, washed with water, dried in vacuo and recrystallized from toluene.
References:
WO2008/25736,2008,A1 Location in patent:Page/Page column 60-61
615-16-7
407 suppliers
$8.00/10g
161468-57-1
9 suppliers
$75.00/100mg
41120-23-4
21 suppliers
inquiry