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ChemicalBook CAS DataBase List 8-methoxy-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
41505-84-4

8-methoxy-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole synthesis

12synthesis methods
923293-14-5 Synthesis
4-Methoxy-2-(pyridin-3-yl)aniline

923293-14-5
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Yield:-

Steps:

Multi-step reaction with 4 steps
1.1: acetic acid; sodium nitrite / water / 1.5 h / 0 °C / Inert atmosphere
1.2: 0 - 20 °C / Inert atmosphere
2.1: dichloromethane / 20 °C / Inert atmosphere
3.1: ruthenium trichloride hydrate / Isopropyl acetate / 15 h / 80 °C / Inert atmosphere
4.1: sodium tetrahydroborate / methanol; water / 20 - 100 °C / Inert atmosphere

References:

Dong, Huijun;Latka, Regina T.;Driver, Tom G. [Organic Letters,2011,vol. 13,# 10,p. 2726 - 2729]

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