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476371-86-5

(2R,4R)-2-(1,1-Dimethylethyl)-4-[(2E)-1-hydroxy-2-methyl-2-buten-1-yl]-4-methyl-1,3-oxathiolan-5-one synthesis

1synthesis methods
476371-85-4 Synthesis
(2R,4S)-2-(1,1-Dimethylethyl)-4-methyl-1,3-oxathiolan-5-one

476371-85-4
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(2R,4R)-2-(1,1-Dimethylethyl)-4-[(2E)-1-hydroxy-2-methyl-2-buten-1-yl]-4-methyl-1,3-oxathiolan-5-one

476371-86-5
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Yield:476371-86-5 81%

Reaction Conditions:

with lithium diisopropyl amide in tetrahydrofuran at -78;

References:

McFadden, Jill M;Frehywot, Gojeb L;Townsend, Craig A [Organic letters,2002,vol. 4,# 22,p. 3859 - 3862]

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