5-METHYL-4-PHENYLPYRIMIDIN-2-AMINE synthesis
- Product Name:5-METHYL-4-PHENYLPYRIMIDIN-2-AMINE
- CAS Number:61541-77-3
- Molecular formula:C11H11N3
- Molecular Weight:185.23
506-93-4
0 suppliers
$15.00/5mg
536-74-3
316 suppliers
$10.00/1g
93-55-0
0 suppliers
$15.00/25g
61541-77-3
21 suppliers
$45.00/10mg
Yield:61541-77-3 60%
Reaction Conditions:
Stage #1: phenylacetylene;1-phenyl-propan-1-onewith potassium tert-butylate in dimethyl sulfoxide at 100; for 0.5 h;Inert atmosphere;
Stage #2: guanidine nitratewith water in dimethyl sulfoxide at 70; for 4 h;Inert atmosphere;
Stage #3: with potassium hydroxide semihydrate in dimethyl sulfoxide at 70; for 0.5 h;Inert atmosphere;
References:
Schmidt, Elena Yu.;Tatarinova, Inna V.;Protsuk, Nadezhda I.;Ushakov, Igor A.;Trofimov, Boris A. [Journal of Organic Chemistry,2017,vol. 82,# 1,p. 119 - 125]
