1-[2-(4-CHLOROPHENYL)-4-METHYL-1,3-THIAZOL-5-YL]-1-ETHANONE synthesis
- Product Name:1-[2-(4-CHLOROPHENYL)-4-METHYL-1,3-THIAZOL-5-YL]-1-ETHANONE
- CAS Number:54001-07-9
- Molecular formula:C12H10ClNOS
- Molecular Weight:251.73
1694-29-7
117 suppliers
$40.00/10g
2521-24-6
174 suppliers
$15.00/1g
54001-07-9
24 suppliers
$181.00/500mg
Yield:54001-07-9 90%
Reaction Conditions:
in ethanol; for 8 h;
Steps:
4.1.1. General synthesis of 1-(4-methyl-2-(40-substitutedphenylthiazole-5-yl)ethane-1-one derivatives (methodA)
General procedure: According to the Hantzsch method, 3-chloro-2,4-pentandione isadded to the hot solution of aryl thioamide in absolute ethanol(Scheme 1) and boiled for 8 h. After being controlled with TLCwhere the reaction is completed, itwas left to cool, poured into coldwater and neutralized by sodium acetate solution. After the precipiationwas completed, it is taken and dried, crystallized fromethanol [40].
References:
Sahin, Zafer;Biltekin, Sevde Nur;Yurttas, Leyla;Berk, Barkin;?zhan, Ya?mur;Sipahi, Hande;Gao, Zhan-Guo;Jacobson, Kenneth A.;Demirayak, ?eref [European Journal of Medicinal Chemistry,2021,vol. 212,art. no. 113125]
![2,4-Pentanedione, 3-[[(4-methylphenyl)sulfonyl]oxy]-](/CAS/20180601/GIF/81447-35-0.gif)
81447-35-0
0 suppliers
inquiry
2521-24-6
174 suppliers
$15.00/1g
54001-07-9
24 suppliers
$181.00/500mg
3043-28-5
15 suppliers
$45.00/50mg
2521-24-6
174 suppliers
$15.00/1g
54001-07-9
24 suppliers
$181.00/500mg
![Ethanone, 1-[2-(4-chlorophenyl)-4-methyl-5-thiazolyl]-2-diazo-](/CAS/20211123/GIF/54001-29-5.gif)
54001-29-5
0 suppliers
inquiry
54001-07-9
24 suppliers
$181.00/500mg
54001-22-8
11 suppliers
inquiry
54001-07-9
24 suppliers
$181.00/500mg