一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

58791-82-5

5-AMINO-1-(4-CHLOROPHENYL)-3-METHYL-1H-PYRAZOLE-4-CARBONITRILE synthesis

1synthesis methods
1073-70-7 Synthesis
4-Chlorophenylhydrazine hydrochloride

1073-70-7
529 suppliers
$5.00/10g

5417-82-3 Synthesis
(1-ETHOXYETHYLIDENE)MALONONITRILE

5417-82-3
126 suppliers
$9.00/1g

-

Yield: 86%

Reaction Conditions:

with sodium acetate in ethanol for 1 h;Reflux;

Steps:

General Procedure for the synthesis of compounds 5-amino-1-aryl-3-methyl-1H-pyrazole-4-carbonitrile 2a-m.
General procedure: Arylhydrazine hydrochlorides (0.01mol) were reacted with (1-ethoxyethylidene)malononitrile (0.01 mol) and sodium acetate (0.02mol) in ethanol (40mL), under reflux, during 1h. After, the mixture was poured in cold water and the precipitate formed was filtered out and recrystallized from ethanol/water. The reactions were accomplished by means of TLC using silica gel plate with fluorescent indicator and hexane/ethyl acetate(1:1) as eluent.

References:

Faria, Jéssica V.;Dos Santos, Maurício S.;Bernardino, Alice M.R.;Becker, Klaus M.;Machado, Gérzia M.C.;Rodrigues, Raquel F.;Canto-Cavalheiro, Marilene M.;Leon, Leonor L. [Bioorganic and Medicinal Chemistry Letters,2013,vol. 23,# 23,p. 6310 - 6312] Location in patent:supporting information

5-AMINO-1-(4-CHLOROPHENYL)-3-METHYL-1H-PYRAZOLE-4-CARBONITRILE Related Search:

西宁市| 宝山区| 项城市| 前郭尔| 南部县| 潢川县| 偏关县| 穆棱市| 古田县| 广东省| 荃湾区| 望江县| 黎城县| 甘洛县| 太仓市| 淅川县| 陆丰市| 衡阳市| 绥宁县| 长阳| 阿图什市| 巴青县| 梁山县| 宁波市| 顺平县| 东至县| 苍南县| 周至县| 嘉荫县| 确山县| 上蔡县| 苏尼特右旗| 丰宁| 嘉黎县| 屯昌县| 临高县| 桐柏县| 霍城县| 绍兴县| 柞水县| 南溪县|