6-BroMo-5-Methyl-2-pyridinaMine synthesis
- Product Name:6-BroMo-5-Methyl-2-pyridinaMine
- CAS Number:89466-17-1
- Molecular formula:C6H7BrN2
- Molecular Weight:187.04
442129-37-5
169 suppliers
$11.00/100mg
89466-17-1
114 suppliers
$24.00/250mg
Yield:89466-17-1 91%
Reaction Conditions:
with phosphorus tribromide at 140; for 6 h;
Steps:
10 Example 10:
3.4 g of chloride IA was added to 10 ml of phosphorus tribromide and heated to 140 degrees.After 6 hours of reaction, the TLC reaction was complete, dropped to ambient temperature, and slowly added to crushed ice.Add 40% sodium hydroxide to adjust the pH to 10, a large amount of solids are precipitated, filtered, and the filter cake is washed with 20 ml of water.The product IB 4g was obtained in a yield of 91%.
References:
Shandong Tefaman Pharmaceutical Co., Ltd.;Chinese Academy Of Sciences Shanghai Pharmaceutical Institute;Jiang Xiangrui;Chen Hua;Zhang Junchi;Shen Jingshan CN108658851, 2018, A Location in patent:Paragraph 0071; 0072; 0073
19230-57-0
46 suppliers
$90.00/100mg
89466-17-1
114 suppliers
$24.00/250mg
19230-57-0
46 suppliers
$90.00/100mg
442129-37-5
169 suppliers
$11.00/100mg
89466-17-1
114 suppliers
$24.00/250mg
3430-17-9
459 suppliers
$4.00/5g
89466-17-1
114 suppliers
$24.00/250mg
936727-56-9
2 suppliers
inquiry
89466-17-1
114 suppliers
$24.00/250mg