(R)-(R)-1-methylpyrrolidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate(WXC03446) synthesis
- Product Name:(R)-(R)-1-methylpyrrolidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate(WXC03446)
- CAS Number:616866-21-8
- Molecular formula:C18H25NO3
- Molecular Weight:303.4
894795-19-8
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Yield:-
Steps:
Multi-step reaction with 3 steps
1.1: lithium hexamethyldisilazane / hexane; tetrahydrofuran / 1 h / -78 °C
1.2: 16 h / -78 - 20 °C
2.1: potassium hydroxide; water / methanol / 4 h / 65 °C
3.1: 1,1'-carbonyldiimidazole / toluene
References:
WO2018/26869,2018,A1
131237-81-5
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616866-21-8
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