7-Nitrogramine synthesis
- Product Name:7-Nitrogramine
- CAS Number:1654-34-8
- Molecular formula:C11H13N3O2
- Molecular Weight:219.24
50-00-0
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6960-42-5
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124-40-3
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1654-34-8
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$375.00/1g
Yield:-
Reaction Conditions:
in water at 20; for 72 h;
Steps:
39.A
A mixture of 7-nitro-lH-indole (3 g, 18.5 mmol), 40% aqueous dimethylamine (3.12 mL, 27.7 mmol) and 37% aqueous formaldehyde (1.57 mL, 19.3 mmol) was stirred for three days at ambient temperature. The reaction mixture was diluted with U2O (20 mL) followed 15% aqueous νaOη (200 mL) and extracted with CηCI3 (3 x 200 mL). The combined organic extracts were dried over νa2SC>4, filtered, and concentrated in vacuo to give the title compound in sufficient purity for use in the next step. MS: r?/z= l81 (M + l).
References:
WO2007/61692,2007,A2 Location in patent:Page/Page column 117
6960-42-5
254 suppliers
$10.00/1g
51-80-9
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$21.00/1mL
1654-34-8
20 suppliers
$375.00/1g