(E)-N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl)-4-(diMethylaMino)but-2-enaMide synthesis
- Product Name:(E)-N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl)-4-(diMethylaMino)but-2-enaMide
- CAS Number:848133-88-0
- Molecular formula:C18H19ClN4O2
- Molecular Weight:358.82
Yield:848133-88-0 7.97 g
Reaction Conditions:
in 1-methyl-pyrrolidin-2-one at 0 - 20; for 2.5 h;
References:
Tsou, Hwei-Ru;Overbeek-Klumpers, Elsebe G.;Hallett, William A.;Reich, Marvin F.;Floyd, M. Brawner;Johnson, Bernard D.;Michalak, Ronald S.;Nilakantan, Ramaswamy;Discafani, Carolyn;Golas, Jonathan;Rabindran, Sridhar K.;Shen, Ru;Shi, Xiaoqing;Wang, Yu-Fen;Upeslacis, Janis;Wissner, Allan [Journal of Medicinal Chemistry,2005,vol. 48,# 4,p. 1107 - 1131]
214476-09-2
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