一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List Carbamic acid,N-[4-chloro-3-(teifluoromethyl)phenyl]-,phenyl ester
871555-75-8

Carbamic acid,N-[4-chloro-3-(teifluoromethyl)phenyl]-,phenyl ester synthesis

1synthesis methods
1885-14-9 Synthesis
Phenyl chloroformate

1885-14-9
346 suppliers
$10.00/1g

Carbamic acid,N-[4-chloro-3-(teifluoromethyl)phenyl]-,phenyl ester

871555-75-8
21 suppliers
inquiry

-

Yield:871555-75-8 95%

Reaction Conditions:

with triethylamine in dichloromethane at 5 - 20; for 2 h;

Steps:

1 Example 1: Synthesis of phenyl N-(4-chloro-3-(trifluoromethyl)phenyl)carbamate (3)

Add 4-chloro-3-(trifluoromethyl)aniline (2) (195.5 g) and triethylamine (202.4g) to dichloromethane (1000 mL), cool the system to 5, and dropwise add phenyl chloroformate(187.8g), after dripping, warm to room temperature and stir for 2h. After the reaction, the system is diluted with dichloromethane (1500ml), water (2000ml) is added, and the liquids are separated. The organic phase is sequentially water (1000mL) and saturated chlorine Wash with sodium chloride solution (1000ml), dry with anhydrous sodium sulfate, concentrate under reduced pressure, and recrystallize (ethyl acetate/n-hexane=1/10 weight ratio) to obtain 286.5 g of compound 3 with a yield of 95%.This step uses the dichloromethane/triethylamine system to replace the N,N-dimethylformamide/pyridine system, avoids the use of more toxic pyridine, simplifies the post-treatment method, does not use the hydrochloric acid aqueous solution for treatment, reduces the cost and reduces Discharge of waste liquid.

References:

CN111718294,2020,A Location in patent:Paragraph 0016-0017

Carbamic acid,N-[4-chloro-3-(teifluoromethyl)phenyl]-,phenyl ester Related Search:

岳阳市| 合作市| 疏勒县| 封开县| 临城县| 乌苏市| 汨罗市| 石屏县| 固镇县| 台北县| 安顺市| 翁源县| 泗洪县| 沧州市| 都安| 濮阳市| 五莲县| 河东区| 德惠市| 静乐县| 云梦县| 夏河县| 呼玛县| 河南省| 大悟县| 普宁市| 江达县| 资兴市| 江口县| 进贤县| 远安县| 甘德县| 柳州市| 奉节县| 鄢陵县| 淅川县| 武胜县| 万载县| 江阴市| 高平市| 潜江市|