Benzene, 1-Methoxy-4-[[(Methylthio)Methoxy]Methyl]- synthesis
3synthesis methods
- Product Name:Benzene, 1-Methoxy-4-[[(Methylthio)Methoxy]Methyl]-
- CAS Number:88023-83-0
- Molecular formula:C10H14O2S
- Molecular Weight:198.28
Yield:88023-83-0 95%
Reaction Conditions:
Stage #1: 4-Methoxybenzyl alcoholwith sodium hydride;sodium iodide in tetrahydrofuran at 0 - 20;Inert atmosphere;
Stage #2: chloro-methylsulfanyl-methane in tetrahydrofuran at 0 - 20; for 12 h;
References:
Nishikawa, Keisuke;Nakahara, Hiroshi;Shirokura, Yousuke;Nogata, Yasuyuki;Yoshimura, Erina;Umezawa, Taiki;Okino, Tatsufumi;Matsuda, Fuyuhiko [Organic Letters,2010,vol. 12,# 5,p. 904 - 907] Location in patent:supporting information; experimental part
