(9-ANTHRYLMETHYLENE)MALONONITRILE synthesis
- Product Name:(9-ANTHRYLMETHYLENE)MALONONITRILE
- CAS Number:55490-87-4
- Molecular formula:C18H10N2
- Molecular Weight:254.29
642-31-9
109-77-3
55490-87-4
GENERAL METHODS: A mixture of 9-anthracenecarboxaldehyde (10.0 mmol), malononitrile (11.0 mmol) and pyridine (10.0 mmol) was stirred for 6 hours at 95 °C. The reaction process was monitored by thin layer chromatography (TLC). After completion of the reaction, water (10 mL) was added to the reaction mixture and extracted with dichloromethane (3 x 10 mL). The organic layers were combined and dried with anhydrous sodium sulfate, followed by evaporation of the solvent under vacuum. The crude product was purified by column chromatography using hexane as eluent, resulting in (9-anthracenemethylene)malononitrile (1a-m), which was structurally characterized.
Yield:55490-87-4 98%
Reaction Conditions:
with C88H68Cl4Hg2N4O4P4 in methanol at 60; for 4 h;Catalytic behavior;Knoevenagel Condensation;
References:
Pachisia, Sanya;Gupta, Rajeev [Crystal Growth and Design,2019,vol. 19,# 11,p. 6039 - 6047]
