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ChemicalBook CAS DataBase List Apixaban Impurity 17
1423803-24-0

Apixaban Impurity 17 synthesis

7synthesis methods
473927-63-8 Synthesis
Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate

473927-63-8
147 suppliers
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Apixaban Impurity 17

1423803-24-0
55 suppliers
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-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: triethylamine / ethyl acetate / 6 h / 75 - 80 °C
2: ammonium chloride; iron / water; methanol / 5 h / 65 - 70 °C
3: ammonia / methanol / 15 h / 60 - 65 °C / Autoclave

References:

CADILA HEALTHCARE LIMITED;DWIVEDI, Shriprakash Dhar;SINGH, Kumar Kamlesh;TANDON, Nitin;WARE, Digambar WO2014/203275, 2014, A2

503615-03-0 Synthesis
3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one

503615-03-0
353 suppliers
$31.00/1g

Apixaban Impurity 17

1423803-24-0
55 suppliers
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