一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List Azatadine
3964-81-6

Azatadine synthesis

7synthesis methods
38092-89-6 Synthesis
N-Methyl Desloratadine

38092-89-6
276 suppliers
$5.00/100mg

-

Yield: 87.5%

Reaction Conditions:

with palladium 10% on activated carbon;hydrogen;acetic acid in ethanol at 60; for 20 h;Solvent;Temperature;Reagent/catalyst;

Steps:

1-4 The loratadine impurity (Formula II) is prepared using the following steps:
To a 100mL three-necked flask, add methylloratadine (3.25g, 10mmol, 1.0eq) and ethanol (25mL), then add acetic acid (1.2g, 20mmol, 2.0eq) and 10% palladium on carbon (1.60g, 1.5mmol) , 0.15eq). Then evacuate, replace with hydrogen three times, and finally raise the temperature to 60 ° C in a hydrogen balloon atmosphere, stir the reaction for 20 hours, drop to room temperature, filter to remove the palladium carbon, concentrate, and the residue is purified by silica gel column chromatography to obtain loratadine impurities 2.54g, yield 87.5%, HPLC purity 99.57%.

References:

Shenzhen Xianggen Biological Technology Co., Ltd.;He Dongmei;Li Fanglin;Zhuang Shibin;Peng Jinan CN110845475, 2020, A Location in patent:Paragraph 0029-0052

Azatadine Related Search:

林西县| 三亚市| 蓝田县| 若尔盖县| 葫芦岛市| 翼城县| 阿拉善右旗| 肇东市| 清丰县| 抚远县| 科技| 乐至县| 金华市| 哈密市| 叶城县| 赞皇县| 稻城县| 昌平区| 灵山县| 临江市| 兴义市| 张家港市| 白水县| 正镶白旗| 商洛市| 康保县| 集安市| 呼玛县| 陈巴尔虎旗| 石首市| 沂南县| 项城市| 奎屯市| 新巴尔虎左旗| 安塞县| 弥勒县| 东兴市| 环江| 济阳县| 镇江市| 木里|