Bis(4-bromophenyl) ether synthesis
- Product Name:Bis(4-bromophenyl) ether
- CAS Number:2050-47-7
- Molecular formula:C12H8Br2O
- Molecular Weight:328
101-84-8
2050-47-7
The general procedure for the synthesis of 4,4'-dibromodiphenyl ether from diphenyl ether was as follows: in a four-necked round-bottomed flask fitted with a stirrer, condenser, dropping funnel and thermometer, diphenyl ether (170 g, 1.0 mol), 1,2-dichloroethane (EDC) (300 ml), water (200 ml) and NaBrO3 (55 g, 0.36 mol) were added. Bromine (176 g, 1.1 mol) was slowly added dropwise to the stirred mixture for 1 h at 25 °C. No significant HBr gas was released during the reaction. The reaction progress was monitored by gas chromatography (GC). After two hours of reaction, the diphenyl ether was completely converted to 4,4'-dibromodiphenyl ether. The reaction was stopped and the phases were separated to give the crude product 4,4'-dibromodiphenyl ether (324.8 g) in 99% yield and 99.5% selectivity.
106-41-2
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2050-47-7
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Yield:2050-47-7 82%
Reaction Conditions:
with titania nanoparticles supported on silica for 0.333333 h;
Steps:
2 Example 2 Preparation of dibromo diphenylether-18
SiO2-TiO2 (0.05 g) and p-bromophenol (1.73 g) were mixed well in a mortar,Grinding for 20 minutes,The product was separated by column chromatography on silica gel using n-hexane as eluant to give 1.34 g of a white solid in 82% yield.
References:
Shandong Analysis Beta Center;Ji Wenhua;Zhao Rusong;Wang Xiao;Geng Yanling;Wang Xia CN106957218, 2017, A Location in patent:Paragraph 0048-0050
101-84-8
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2050-47-7
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589-87-7
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2050-47-7
265 suppliers
$6.00/5g