BUTTPARK 77\08-25 synthesis
- Product Name:BUTTPARK 77\08-25
- CAS Number:874801-60-2
- Molecular formula:C14H17N3O3S
- Molecular Weight:307.37
3473-63-0
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$5.00/25g
![2-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRIDINE-3,6-DICARBOXYLIC ACID 6-TERT BUTYL ESTER 3-ETHYL ESTER](/CAS/GIF/193537-14-3.gif)
193537-14-3
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$9.00/250mg
874801-60-2
26 suppliers
$84.00/100mg
Yield:874801-60-2 95%
Reaction Conditions:
in N,N-dimethyl-formamide at 100; for 12 h;
Steps:
Experimental procedure for the synthesis of linked N - Boctetrahydropyrido thienopyrimidine derivatives:
General procedure: To the starting material tert-butyl4-oxopiperidine-1-carboxylate ( 14 , 1 mmol) ethylcyano acetate ( 2 , 1 mmol), Sulphur powder (1 mmol), 10 mL of ethanol and TEA (1 mmol) was added and re- fluxed for 10-12 h, after the completion of reaction intermediate 15 was obtained to which formamidine acetate (1.5 mmol) and 10 mL of DMF was added and heated at 100 °C for 12 h to procure intermediate 16 . Then, intermediate 16 was treated with equimo- lar amounts of aryl halides ( 17a-f ), K 2 CO 3 which was used as base and 5 mL of DMF and the reaction for carried at room tempera- ture for 12 h. After cooling aryl substituted N -Boc tetrahydropyrido thienopyrimidine analogues 18a-f were obtained.
References:
Malasala, Satyaveni;Polomoni, Anusha;Ahmad, Md. Naiyaz;Shukla, Manjulika;Kaul, Grace;Dasgupta, Arunav;Chopra, Sidharth;Nanduri, Srinivas [Journal of Molecular Structure,2021,vol. 1234,art. no. 130168]
463-52-5
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193537-14-3
127 suppliers
$9.00/250mg
874801-60-2
26 suppliers
$84.00/100mg
79099-07-3
0 suppliers
$5.00/5g
874801-60-2
26 suppliers
$84.00/100mg