Cediranib Maleate synthesis
- Product Name:Cediranib Maleate
- CAS Number:857036-77-2
- Molecular formula:C25H27FN4O3·C4H4O4
- Molecular Weight:566.59
574745-75-8
23 suppliers
$316.00/100mg
857036-77-2
80 suppliers
inquiry
Yield:-
Steps:
Multi-step reaction with 3 steps
1.1: palladium 10% on activated carbon; hydrogen / 1-methyl-pyrrolidin-2-one / 5 h / 20 °C / 760.05 Torr
2.1: potassium carbonate / 1-methyl-pyrrolidin-2-one / 2 h / 80 °C
3.1: pyrographite / isopropyl alcohol / 1 h / Inert atmosphere; Reflux
3.2: 0.08 h / Inert atmosphere; Reflux
References:
Hangzhou Pushai Pharmaceutical Technology Co., Ltd.;Zhu, Tao;Sheng, XiaoHong;Sheng, xiaoxia CN105461698, 2016, A