一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List CHEMBRDG-BB 4010855
894852-67-6

CHEMBRDG-BB 4010855 synthesis

2synthesis methods
-

Yield:894852-67-6 71%

Reaction Conditions:

Stage #1: 2-formyl-3-methylindole;methylamine in methanol;ethanol; for 5 h;
Stage #2: with sodium tetrahydroborate in methanol;ethanol at 0 - 20;
Stage #3: with water in methanol;ethanol at 0;

Steps:

60.a

a) Preparation of 3-methyl-2-(methylaminomethyl)indole; Methylamine (0.34 niL, 8.4 mmol, 33% in ethanol) was added to a solution of 3- methylindole-2-carboxaldehyde (447 mg, 2.8 mmol) in methanol (10 mL) and stirred for 5 hours. Sodium borohydride (104 mg, 2.8 mmol) was slowly added at 00C. The resultant mixture was warmed to room temperature and stirred overnight. Water (2 mL) was added slowly at 0 0C and the mixture was evaporated to a paste. The paste was partitioned between water (2 niL) and dichloromethane (15 mL). The layers were separated and the aqueous layer was extracted with dichloromethane (2 x 15 mL). The combined organic phases were dried and evaporated to afford title compound (348 mg, 71%). 1H NMR (400 MHz, DMSO-de): 10.63 (s, IH), 7.38 (d, J = 7.7 Hz, IH), 7.25 (d, J = 8.0 Hz, IH), 6.99 (t, J - 8.0 Hz, IH), 6.92 (t, J = 6.6 Hz, IH), 3.73 (s, 2H), 2.25 (s, 3H), 2.19 (s, 3H)

References:

WO2007/53131,2007,A2 Location in patent:Page/Page column 166-167

CHEMBRDG-BB 4010855 Related Search:

建宁县| 富民县| 正镶白旗| 枣阳市| 仁寿县| 乌兰县| 公安县| 延吉市| 宣恩县| 苗栗市| 阿拉善左旗| 曲周县| 兴宁市| 新平| 宝坻区| 罗山县| 延津县| 偃师市| 大渡口区| 青海省| 绩溪县| 鹤壁市| 客服| 阿合奇县| 宁远县| 余江县| 九龙坡区| 和龙市| 贺兰县| 桐柏县| 皮山县| 南昌市| 宜兰市| 博罗县| 望谟县| 开化县| 天门市| 凤山县| 明水县| 宝鸡市| 安岳县|