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ChemicalBook CAS DataBase List Clobetasol propionate
25122-46-7

Clobetasol propionate synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: triethylamine; dmap / chloroform / 50 °C
2: 5,5-dibromohydantoin; perchloric acid / acetone / -5 - 5 °C
3: hydrogen fluoride / chloroform; water / -40 °C

References:

CN107793462,2018,A

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