Dihydrocapsaicin synthesis
- Product Name:Dihydrocapsaicin
- CAS Number:19408-84-5
- Molecular formula:C18H29NO3
- Molecular Weight:307.43
404-86-4
694 suppliers
$25.00/500mg
19408-84-5
329 suppliers
$24.00/5 mg
Yield:19408-84-5 85%
Reaction Conditions:
with platinum (IV) oxide hydrate;hydrogen in methanol at 20; under 760.051 Torr; for 7 h;Solvent;
Steps:
1 Example 1
The preparation method of the high-purity dihydrocapsaicin monomer comprises the following steps:
8 g of the raw natural capsaicin (the sum of the capsaicin and dihydrocapsaicin contents of 95%) was placed in 120 ml of methanol and the mixture was stirred at room temperature for 1 hour to obtain a natural capsaicin solution. 400 mg of platinum oxide hydrate was added to the natural capsaicin solution, and the mixture was subjected to hydrogenation at room temperature for 6 hours at room temperature, filtered through celite and concentrated to a colorless. The product was dissolved in 400 ml of a purified product at 55°C using a mixture of 300 ml of acetonitrile and 100 ml of methyl tert-butyl ether. The mixture was poured into a crystallizer and allowed to stand and crystallize at a crystallization temperature of -10°C; the precipitated crystals were separated by filtration, and the filter cake was pressed and vacuum dried for 3 hours at 50 ° C under a pressure of 0. 002 MPa to obtain 6. 8 g of a white spicy high purity dihydrocapsaicin monomer product, The mass yield of dihydro capsaicin monomer was 85%. The product purity of dihydro capsaicin was 99.3% by HPLC.
References:
Shanghai Aladdin Biochemical Technology Co., Ltd;Ling, Qing;Liu, Yunying CN105418445, 2016, A Location in patent:Paragraph 0018; 0019; 0020
1196-92-5
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$544.00/500g
5963-14-4
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$47.00/100mg
19408-84-5
329 suppliers
$24.00/5 mg
25775-90-0
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$50.00/50mg
19408-84-5
329 suppliers
$24.00/5 mg
502-44-3
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$5.00/25g
19408-84-5
329 suppliers
$24.00/5 mg
6654-36-0
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$20.00/250mg
19408-84-5
329 suppliers
$24.00/5 mg