DIPHENYL-D10 ETHER synthesis
- Product Name:DIPHENYL-D10 ETHER
- CAS Number:93952-05-7
- Molecular formula:C12H10O
- Molecular Weight:170.21
101-84-8
611 suppliers
$5.00/25g
93952-05-7
23 suppliers
$505.51/5MG
Yield:93952-05-7 100%
Reaction Conditions:
with water-d2;isopropyl alcohol in n-heptane at 120;Flow reactor;
Steps:
General procedures (GP) GP-B; 2-PrOH/heptane mixed solvent system (Table 6)
General procedure: A solution of the substrate (0.5 mmol) in a mixed solvent of 2-PrOH/heptane and D2O were mixed using a mixer and pumped by different two syringe pumps (YMC, YSP-101) at a flow rate of 0.03 mL/min and 0.07 mL/min into the catalyst-packed cartridge (4.6×50 mm, SUS-316) at 120 °C. The cartridge was washed with 10 mL of a mixed solvent of 2-PrOH/heptane and D2O. The whole reaction mixture was collected and extracted with ethyl acetate (40 mL×2). The combined organic layers were dried over Na2SO4 and concentrated in vacuo to give the corresponding deuterium-labeled product.
References:
Park, Kwihwan;Ito, Naoya;Yamada, Tsuyoshi;Sajiki, Hironao [Bulletin of the Chemical Society of Japan,2021,vol. 94,# 2,p. 600 - 605] Location in patent:supporting information
4165-57-5
192 suppliers
$61.00/5ml
13127-88-3
96 suppliers
$66.00/1g
93952-05-7
23 suppliers
$505.51/5MG