ETHYL 2-CARBOETHOXYBENZOYLFORMATE synthesis
1synthesis methods
- Product Name:ETHYL 2-CARBOETHOXYBENZOYLFORMATE
- CAS Number:732249-79-5
- Molecular formula:C13H14O5
- Molecular Weight:250.25
Yield:732249-79-5 89 %Chromat.
Reaction Conditions:
Stage #1: ethyl 2-iodobenzoatewith phenyllithium in diethyl ether;cyclohexane at -60; for 1.13889E-05 h;Flow reactor;
Stage #2: oxalic acid diethyl ester in diethyl ether;cyclohexane at -60; for 0.000466667 h;Flow reactor;
Stage #3: with water;acetic acid in tetrahydrofuran;hexane;Temperature;
References:
Nagaki, Aiichiro;Ichinari, Daisuke;Yoshida, Jun-Ichi [Chemical Communications,2013,vol. 49,# 31,p. 3242 - 3244] Location in patent:supporting information