Ethyl 2-MethoxyethaniMidoate hydrochloride synthesis
- Product Name:Ethyl 2-MethoxyethaniMidoate hydrochloride
- CAS Number:42945-65-3
- Molecular formula:C5H12ClNO2
- Molecular Weight:153.6073
64-17-5
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42945-65-3
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Yield:42945-65-3 87%
Reaction Conditions:
with hydrogenchloride in diethyl ether at -10 - 20; for 17 h;
Steps:
85.1
85 Step 1. Hydrochloric acid gas is bubbled through a solution of methoxyacetonitrile (26 g, 0.37 mol) in EtOH (22 mL) and diethyl ether (118 mL), which is chilled to -1O0C for twenty minutes. The reaction vessel is capped and stirred for 17 hours at ambient temperature. The mixture is cooled to -100C. The solid that forms is collected by filtration, washed with diethyl ether and air dried to afford 2-methoxy- acetimidic acid ethyl ester hydrochloride (49.3 g, 87%) as a solid.
References:
WO2006/44732,2006,A2 Location in patent:Page/Page column 212-213
1738-36-9
168 suppliers
$20.00/5g
42945-65-3
14 suppliers
$45.00/5mg