Flumetramide synthesis
- Product Name:Flumetramide
- CAS Number:7125-73-7
- Molecular formula:C11H10F3NO2
- Molecular Weight:245.2
383-53-9
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Yield:-
Steps:
Multi-step reaction with 4 steps
1.1: hexamethylenetetramine / chloroform / 16 h / 20 °C
1.2: 12 h / 20 °C
2.1: sodium tetrahydroborate / methanol / 0.5 h / 0 °C
3.1: triethylamine / dichloromethane / 1 h / 0 °C
4.1: potassium tert-butylate / tetrahydrofuran / 1 h / 0 - 20 °C
References:
Micheli, Fabrizio;Cremonesi, Susanna;Semeraro, Teresa;Tarsi, Luca;Tomelleri, Silvia;Cavanni, Paolo;Oliosi, Beatrice;Perdon, Elisabetta;Sava, Anna;Zonzini, Laura;Feriani, Aldo;Braggio, Simone;Heidbreder, Christian [Bioorganic and Medicinal Chemistry Letters,2016,vol. 26,# 4,p. 1329 - 1332]
![Ethanone, 2-amino-1-[4-(trifluoromethyl)phenyl]-](/CAS/20210305/GIF/771582-55-9.gif)
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339-58-2
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