Flumezapine synthesis
1synthesis methods
- Product Name:Flumezapine
- CAS Number:61325-80-2
- Molecular formula:C17H19FN4S
- Molecular Weight:330.42
![4H-Thieno[2,3-b][1,5]benzodiazepin-4-one, 7-fluoro-5,10-dihydro-2-methyl-](/CAS/20210305/GIF/61325-55-1.gif)
Yield:61325-80-2 35%
Reaction Conditions:
with titanium tetrachloride in various solvent(s) at 120; for 2 h;
References:
Chakrabarti, Jiban K.;Horsman, Linda;Hotten, Terrence M.;Pullar, Ian A.;Tupper, David E. [Journal of Medicinal Chemistry,1980,vol. 23,# 8,p. 878 - 884]