Fozivudine synthesis
- Product Name:Fozivudine
- CAS Number:141790-23-0
- Molecular formula:C35H64N5O8PS
- Molecular Weight:745.958
1064563-36-5
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134542-59-9
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141790-23-0
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![Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-](/CAS/20210305/GIF/1000210-73-0.gif)
1000210-73-0
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Yield:-
Steps:
14.2 (2)
Phosphoric acid (2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester (R)-2-decyloxy-3-dodecylsulfanyl-propyl ester and Phosphoric acid (2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester (R,S)-2-decyloxy-3-dodecylsulfanyl-propyl ester were prepared by similar procedures using (R)-1-dodecylthio-2-decyloxy-propan-3-ol and (R,S)-1-dodecylthio-2-decyloxy-propan-3-ol respectively in place of (R)-1-dodecylthio-2-decyloxy-propan-3-ol.
References:
ARDEA BIOSCIENCES, INC. US2008/249066, 2008, A1