Gapicomine synthesis
- Product Name:Gapicomine
- CAS Number:1539-39-5
- Molecular formula:C12H13N3
- Molecular Weight:199.25
100-48-1
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1539-39-5
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$71.00/100mg
Yield: 92%
Reaction Conditions:
with sodium tetrahydroborate;La0.5Ca0.5CoO3 in methanol at 40; under 760.051 Torr; for 0.333333 h;chemoselective reaction;
Steps:
General procedure for the reduction of nitriles into their correspondingsec-amines.
General procedure: To a stirring mixture of the appropriate nitrile (1 mmol) and nanosized La0.5Ca0.5CoO3 perovskite (1 mol%, 1.9 mg) in MeOH (5 ml) at 40C, NaBH4 (2 mmol, 0.08 g) was added portion wise. After the completion of the reaction which was monitored by TLC using CHCl3: MeOH (30:1) as eluent, the catalyst was centrifuged off and the solvent was evaporatedunder reduced pressure. To the resulting oily liquid, water (20 ml) was added and the mixture was extracted with CH2Cl2 (2 × 20 ml). The organic layer was dried over anhydrous Na2SO4 and the solvent was evaporated under reduced pressure to afford the pure products.
References:
Bavandi, Hossein;Shiri, Ali;Tavakkoli, Haman [Journal of the Chilean Chemical Society,2017,vol. 62,# 1,p. 3330 - 3334]
696-54-8
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3731-53-1
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1539-39-5
40 suppliers
$71.00/100mg
3731-53-1
291 suppliers
$6.00/5g
1539-39-5
40 suppliers
$71.00/100mg
3731-53-1
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2038-57-5
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![Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-](/CAS/20210305/GIF/1000210-73-0.gif)
1000210-73-0
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1539-39-5
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$71.00/100mg
872-85-5
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3731-53-1
291 suppliers
$6.00/5g
1539-39-5
40 suppliers
$71.00/100mg