一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List β-Cyclohexyl-L-alanine methyl ester hydrochloride
17193-39-4

β-Cyclohexyl-L-alanine methyl ester hydrochloride synthesis

8synthesis methods
Methanol

67-56-1

H-CHA-OH HCL

25528-71-6

H-CHA-OME HCL

17193-39-4

For the synthesis of compounds 2a, 2c-2g, a slightly modified literature method [1] was used. The procedure was as follows: (S)-2-amino-3-cyclohexylpropanoic acid hydrochloride (32.2 mmol) was dissolved in anhydrous methanol (100 mL) under stirring conditions, and the temperature of the reaction system was maintained between -10 and -5 °C, and thionyl chloride (64.4 mmol) was added slowly dropwise. After the dropwise addition, the reaction mixture was stirred continuously at room temperature for 16 hours. After completion of the reaction, the reaction solution was concentrated to dryness by rotary evaporator. The resulting crude product was dissolved with ethyl acetate (EtOAc) and the solid product was subsequently collected by filtration. The collected solid was dried under reduced pressure to afford (S)-methyl 2-amino-3-cyclohexylpropanoate hydrochloride as a white crystalline powder, all in higher than 80% yield. The melting point of the product and the 1H and 13C NMR spectroscopic data in D2O were in agreement with those reported in the literature [20] for the characterization of the compound.

-

Yield:17193-39-4 97%

Reaction Conditions:

with chloro-trimethyl-silaneHeating;

References:

Fossey, John S.;Jones, Geraint;Motevalli, Majid;Nguyen, Huy V.;Richards, Christopher J.;Stark, Mark A.;Taylor, Helen V. [Tetrahedron Asymmetry,2004,vol. 15,# 13,p. 2067 - 2073]

β-Cyclohexyl-L-alanine methyl ester hydrochloride Related Search:

和田市| 通州市| 阳原县| 永定县| 诏安县| 澄城县| 湘潭市| 西和县| 桃源县| 德化县| 聂拉木县| 长海县| 麟游县| 五莲县| 名山县| 红桥区| 乐安县| 沁水县| 锡林郭勒盟| 望奎县| 齐河县| 哈尔滨市| 新巴尔虎左旗| 昭平县| 南充市| 申扎县| 蓝田县| 烟台市| 瓦房店市| 台南县| 辽中县| 诸暨市| 原平市| 苍溪县| 永州市| 公主岭市| 什邡市| 铜山县| 曲沃县| 乳源| 德阳市|