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ChemicalBook CAS DataBase List LL P880 beta
41164-59-4

LL P880 beta synthesis

1synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 7 steps
1: 72 percent / p-toluenesulfonic acid / tetrahydrofuran / 1 h / 0 - 5 °C
2: 1) NaH / 1) DMSO, 2h, r.t. 2) DMSO, 12h, r.t.
3: 75 percent / 0.3M aq. HClO4 / acetonitrile / 0.75 h / Ambient temperature
4: 83 percent / Pb(OAc)4 / benzene / 0.33 h / Ambient temperature
6: K2CO3 / acetone / 1) 30 min, 0 deg C, 2) 5h, r.t.
7: 0.61 g / H2 / 10percent Pd-C / methanol / 6 h / 760 Torr

References:

Kirihata, Mitsunori;Ohta, Kazunari;Ichimoto, Itsuo;Ueda, Hiroo [Agricultural and Biological Chemistry,1990,vol. 54,# 9,p. 2401 - 2405]

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