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ChemicalBook CAS DataBase List LY-364947
396129-53-6

LY-364947 synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: lithium bis(trimethylsilyl)amide / tetrahydrofuran / 0.17 h
1.2: tetrahydrofuran / 18 h
2.1: tetrahydrofuran / 48 h
3.1: hydrazine monohydrate / ethanol / 18 h

References:

Sawyer, J. Scott;Anderson, Bryan D.;Beight, Douglas W.;Campbell, Robert M.;Jones, Michael L.;Herron, David K.;Lampe, John W.;McCowan, Jefferson R.;McMillen, William T.;Mort, Nicholas;Parsons, Stephen;Smith, Edward C. R.;Vieth, Michal;Weir, Leonard C.;Yan, Lei;Zhang, Faming;Yingling, Jonathan M. [Journal of Medicinal Chemistry,2003,vol. 46,# 19,p. 3953 - 3956]

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