一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List METHYL 10-HYDROXYDECANOATE
2640-94-0

METHYL 10-HYDROXYDECANOATE synthesis

12synthesis methods
-

Yield: 91.3%

Reaction Conditions:

Stage #1:Methyl 10-undecenoate with ozone in methanol;dichloromethane at -78; for 1 h;
Stage #2: with sodium tetrahydroborate in methanol;dichloromethane at 20; for 8 h;
Stage #3: with water;ammonium chloride

Steps:

7
EXAMPLE 7; Synthesis of Alcohol (24); Methyl 10-undecenoate (1.50 g, 7.56 mmol) in dichloromethane and methanol (45.4 mL, 1:1) was stirred at -78° C. for 1 hour while introducing ozone thereto. Nitrogen gas was introduced thereto for 5 minutes to remove ozone and then thereto was added sodium borohydride (429 mg, 11.4 mmol). The mixture was stirred for 8 hours while gradually rising to room temperature. To the reaction mixture was added an aqueous saturated ammonium chloride solution and after neutralizing, the mixture was concentrated under reduced pressure. The residue was extracted with ethyl acetate and the organic layer was washed with an aqueous saturated sodium chloride solution. The organic layer was dried over anhydrous magnesium sulfate, concentrated under reduced pressure and the residue was purified with silica gel column chromatography (from 25% to 33% ethyl acetate in hexane) to give Alcohol (24) (1.40g, 91.3%). IR (NaCl neat): 3385.38, 1739.95, 1437.10, 1172.83, 1057.09 cm-1 1H NMR (CDCl3, 400 MHz) δ: 3.67 (s, 3H), 3.63 (t, J=6.8 Hz, 2H), 2.30 (t, J=7.6 Hz, 2H), 1.93 (brs, 1H), 1.64 (m, 2H), 1.55 (m, 2H), 1.30 (m, 10H); 13C NMR (CDCl3, 100 MHz) δ: 174.3, 62.8, 51.4, 34.0, 32.7, 29.3, 29.3, 29.1, 29.0, 25.6, 24.8.

References:

Katsumura, Shigeo;Hakogi, Toshikazu;Shigenari, Toshihiko US2005/182265, 2005, A1 Location in patent:Page/Page column 10

METHYL 10-HYDROXYDECANOATE Related Search:

安福县| 东丽区| 响水县| 塘沽区| 榕江县| 顺昌县| 县级市| 大荔县| 西藏| 高雄市| 额敏县| 阿拉善盟| 定边县| 安乡县| 云安县| 德令哈市| 江山市| 丁青县| 红安县| 静海县| 五台县| 育儿| 舒城县| 宁远县| 保德县| 五家渠市| 麟游县| 东港市| 隆尧县| 平江县| 和田市| 凌云县| 江口县| 洪泽县| 永善县| 营山县| 锡林郭勒盟| 博爱县| 平武县| 黎川县| 昆明市|