Methyl 3-methoxy-4-nitrobenzoate synthesis
- Product Name:Methyl 3-methoxy-4-nitrobenzoate
- CAS Number:5081-37-8
- Molecular formula:C9H9NO5
- Molecular Weight:211.17
5368-81-0
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$6.00/1g
5081-37-8
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$50.10/1g
Yield: 88%
Reaction Conditions:
with 3-(ethoxycarbonyl)-1-(5-methyl-5-(nitrosooxy)hexyl)pyridin-1-ium bis(trifluoromethanesulfonyl)imide at 20; for 2 h;Ionic liquid;
Steps:
General procedure for the synthesis of products (1b-30b)
General procedure: To a Schlenk tube were added arene (1 mmol) and TS-N-IL (1.3 mmol). Then the tube was stirred at room temperature under air for the indicated time until complete consumption of starting material as monitored by TLC analysis. After the reaction was finished, the reaction mixture was extracted with ethyl acetate (3 20 mL). The combined extracts were washed with aqueous NaHCO3, dried over anhydrous Na2SO4 and evaporated in a rotary evaporator under reduced pressure. The crude product was purified by filtration through a column chromatography on silica gel employing ethyl acetate-hexane mixture to afford the desired product. The purity of the compound was confirmed by NMR and mass analysis, vide infra.
References:
Chaudhary, Renu;Natarajan, Palani;Rani, Neetu;Sakshi;Venugopalan, Paloth [Tetrahedron Letters,2019] Location in patent:supporting information
67-56-1
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5081-36-7
222 suppliers
$6.00/1g
5081-37-8
132 suppliers
$50.10/1g