Methyl carbazate synthesis
- Product Name:Methyl carbazate
- CAS Number:6294-89-9
- Molecular formula:C2H6N2O2
- Molecular Weight:90.08
616-38-6
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$5.00/5 g
6294-89-9
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$6.00/25g
Yield:6294-89-9 94%
Reaction Conditions:
with hydrazine hydrate at 20 - 50; for 24.5 h;
Steps:
Preparation of methyl hydrazinecarboxylate (2)
A mixture of dimethyl carbonate (1, 45.0 g, 0.50 mol) and hydrazine hydrate (29.4 mL, 0.48 mol) was added into a 250 mL round-bottom flask equipped with a condenser. The reaction mixture was heated to 50 °C, stirred for 30 min, and then stirred at room temperature for 24 h. Water, methanol, and excess dimethyl carbonate were distilled off under reduced pressure. After dryness, a white crystal (2) (42.3 g) was obtained with a yield of 94%, mp 69-70 °C.1H NMR (300 MHz, CDCl3): δ 3.73 (s, 3H, CH3-O), 3.77 (d, 2H,J=1.85Hz, -NH2), 6.09 (s, 1H, -NH).
References:
Zhang, Jing-Peng;Qin, Yao-Guo;Dong, Ya-Wen;Song, Dun-Lun;Duan, Hong-Xia;Yang, Xin-Ling [Chinese Chemical Letters,2017,vol. 28,# 2,p. 372 - 376] Location in patent:supporting information
616-38-6
725 suppliers
$5.00/5 g
6294-89-9
356 suppliers
$6.00/25g
497-18-7
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61985-23-7
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6294-89-9
356 suppliers
$6.00/25g
79-22-1
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6294-89-9
356 suppliers
$6.00/25g