N-BUTYL 4-NITROBENZOATE synthesis
- Product Name:N-BUTYL 4-NITROBENZOATE
- CAS Number:120-48-9
- Molecular formula:C11H13NO4
- Molecular Weight:223.23
Yield:120-48-9 99.1%
Reaction Conditions:
with sulfuric acid at 120; for 12 h;
Steps:
1.1
1 Add 200 g of n-butyl p-nitrobenzoate (0.9 mol), 73.3 g of n-butanol (0.99 mol), and 167 g of p-nitrobenzoic acid (1 mol) to the esterification reactor, and slowly add dropwise with stirring. 1.9 g of concentrated sulfuric acid was added to reflux (120 ± 1 ° C) after heating, and after 12 h of heat preservation reaction, the temperature was raised to 128 ± 1 ° C, and a total of 17.8 g of water was separated. After completion of the reaction, the mixture was cooled to 35 ± 1 ° C, neutralized with a sodium carbonate aqueous solution to pH = 7.5 ± 0.1, and allowed to stand for separation to obtain 421 g of the lower organic relative n-butyl nitrobenzoate, the yield was 99.1%, and the purity was 99.26% (HPLC).
References:
CN110343051,2019,A Location in patent:Paragraph 0014; 0015
201230-82-2
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636-98-6
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201230-82-2
1 suppliers
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71-36-3
1113 suppliers
$14.00/25mL
120-48-9
33 suppliers
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