N-Methylhomopiperazine synthesis
- Product Name:N-Methylhomopiperazine
- CAS Number:4318-37-0
- Molecular formula:C6H14N2
- Molecular Weight:114.19
(1) N-(2-haloethyl)trifluoroacetamide was prepared by reacting with ethyl trifluoroacetate in the presence of a solvent and a catalyst using a 2-haloethylamine compound as an initial raw material;
(2) N-(2-haloethyl)trifluoroacetamide obtained in
59039-76-8
6 suppliers
inquiry
4318-37-0
232 suppliers
$6.00/100mg
Yield:4318-37-0 91.6%
Reaction Conditions:
with palladium 10% on activated carbon;hydrogen in methanol; under 7500.75 Torr; for 4 h;Solvent;
Steps:
1; 2
Weigh 1-benzyl-4-methyl-1,4-homopiperazine (8.05 g, 39.4 mmol),And measure 50mL of methanol into the reaction flask,Weigh 1.6g of 10% Pd/C into the reaction solution, and pass the hydrogen pressure at 1MPa, and react for 4h. After the reaction is complete, suction filtration, concentrate to dryness under reduced pressure, and then distill under reduced pressure to obtain 4.12g of the product. The rate was 91.6%.
References:
CN114957163,2022,A Location in patent:Paragraph 0011; 0043; 0048; 0049; 0054
5441-40-7
95 suppliers
$21.00/250mg
4318-37-0
232 suppliers
$6.00/100mg
![2-[(3-aminopropyl)methylamino]ethanol](/CAS/GIF/41999-70-6.gif)
41999-70-6
47 suppliers
inquiry
4318-37-0
232 suppliers
$6.00/100mg
949-69-9
97 suppliers
$28.60/10MG
4318-37-0
232 suppliers
$6.00/100mg
55186-89-5
123 suppliers
$19.00/250mg
4318-37-0
232 suppliers
$6.00/100mg