一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List Orbifloxacin
113617-63-3

Orbifloxacin synthesis

1synthesis methods
110871-86-8 Synthesis
Sparfloxacin

110871-86-8
371 suppliers
$9.00/1g

-

Yield:113617-63-3 88 g

Reaction Conditions:

Stage #1:sparfloxacin with hydrogenchloride;sodium nitrite in water at 0 - 5;
Stage #2: with tetrafluoroboric acid in water at -10 - 0; for 5 h;
Stage #3:Heating;

Steps:

1.2; 1.3; 1.4 Example 1
(2) the diazotization reaction
In a 500 ml three-neck flask, add sparfloxacin 156.8 g (0.4 mol), mass concentration of 30% hydrochloric acid aqueous solution 105 ml. Under 0-5 °C ice salt bath cooling conditions, slowly drop 12 mol/L sodium nitrite aqueous solution 50 ml (0.6 mol), intense stirring, potassium iodide starch paper test diazotization reaction end point, diazonium salt solution is prepared.
(3) preparation of sparfloxacin tetrafluoroborate salt
The step (1) prepared tetrafluoroboric acid was cooled to 0 °C and added dropwise to the step (2) diazonium salt solution. The dropping ends. At -10 °C placed for 5 hours, separating solid, filtering, washing the solid with ethyl ether, vacuum drying, sparfloxacin tetrafluoroborate salt obtained.
(4) thermal decomposition reaction
The step (3) dried solid was placed into a 500 ml single-mouth flask. In an electric furnace directly heat on an asbestor gauze to carry out thermal decomposition reaction until no gas is produced, get orbifloxacin crude product. And then using anhydrous ethanol heating dissolved, decolorized with active carbon, filtering, the filtrate crystallization, filtration, crystal drying, to obtain the product orbifloxacin 88 g, yield 56%,

References:

Zhejiang University of Technology;Sun Li;Pei Wen;Wang Haibin;Yang Zhenping CN104817533, 2017, B Location in patent:Paragraph 0019; 0022; 0025-0030

FullText

Orbifloxacin Related Search:

遂溪县| 托里县| 花垣县| 郴州市| 桃江县| 玉林市| 嘉鱼县| 冕宁县| 象山县| 利辛县| 合山市| 武城县| 平远县| 宁明县| 积石山| 漳州市| 上高县| 武安市| 高平市| 桂林市| 古交市| 廊坊市| 南华县| 湖北省| 江孜县| 华坪县| 广州市| 斗六市| 罗甸县| 平泉县| 威海市| 垣曲县| 祁门县| 元朗区| 竹山县| 榆中县| 淮阳县| 新龙县| 深水埗区| 长岛县| 丹巴县|