Phthalhydrazide synthesis
- Product Name:Phthalhydrazide
- CAS Number:1445-69-8
- Molecular formula:C8H6N2O2
- Molecular Weight:162.15
85-44-9
784 suppliers
$9.00/5g
1445-69-8
314 suppliers
$7.00/10g
Yield:1445-69-8 97.9%
Reaction Conditions:
with tetrabutylammomium bromide;hydrazine hydrate in 5,5-dimethyl-1,3-cyclohexadiene at 120;Green chemistry;Reagent/catalyst;Temperature;Solvent;
Steps:
1-9 Example 5:
400 g of recovered solvent xylene was added to a 1000 mL four-necked flask equipped with a stirring, a condenser and a thermometer.118.4 g (0.80 mol) of raw material, 1.84 g of phase transfer catalyst tetrabutylammonium bromide, and the temperature was raised to 120 ° C or higher.Adding 60% hydrazine hydrate 73.3g (0.088 mol), while distilling out the azeotrope of solvent xylene and the formed water,After the water is separated into water, the reaction is carried out for 2-3 hours, the reaction is completed, and the mixture is cooled to room temperature. After the reaction is completed,After cooling and suction filtration, 126.9 g of phthaloyl hydrazide was obtained, and the yield was 97.9%.High performance liquid chromatography (HPLC) purity of 98.7%.
References:
Zhonghao (Dalian) Chemical Design Yuan Co., Ltd.;Liu Ende;Wu Cheng;Han Jianguo;Cai Xiaochuan;Zheng Yuzhong;Hu Chengyu;Wang Yidi CN108675962, 2018, A Location in patent:Paragraph 0011-0019
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446292-08-6
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$120.00/25mg
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446292-10-0
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$16.00/100mg
1445-69-8
314 suppliers
$7.00/10g
136918-14-4
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1445-69-8
314 suppliers
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270-75-7
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1445-69-8
314 suppliers
$7.00/10g